Meet the Experts
After receiving her MBA from Yale University in 1994, Brunde Broady worked as a financial analyst and private investor until the birth of her son in 2000. At an early age her son Knute experienced numerous health issues including sleep apnea, swallowing problems ptosis, muscle weakness painful rashes and asthma. After exhausting conventional medical treatment that could provide no diagnosis, she began her own quest for answers. Over the course of several years she began to make the connection between the severity of his symptoms and exposure to certain foods and substances such as food additives, artificial flavorings, food dyes, pesticides and off gassing from plastics. Looking for a link she discovered that all of these substances had a negative impact on Ca²+ATPase, a key enzyme found in every cell in the body. She soon realized that in addition to her son, there were many people that could benefit from her knowledge, because reduced Ca²+ATPase plays a major role in many diseases such as heart failure, cancer, and diabetes. She went on a 10 year quest reading and synthesizing hundreds of scientific journal articles in order to fully understand the subject. She received patents in both the United States and China related to her work on Ca²+ATPase. Her goal now is to share her knowledge with as many people as possible to enable them to make educated decisions in regards to their health and lifestyle.
Dr. Dahl is a former Professor of Neuroscience and Medicinal Chemistry and received his Ph.D. in organic chemistry from the University of California, San Diego as a DuPont pharmaceuticals fellow and has additional training in molecular pharmacology from Stanford University. He has co-authored over 80 scientific publications and is an inventor on over 50 patent applications. For more than a decade, his focus has been on intracellular calcium regulation and Ca2+ATPase. He is one of the top experts in the country.
Currently, Dr. Dahl is the CEO and scientific founder of Neurodon, a privately held biotech company that specializes in developing drugs that target cellular health. He has identified a small molecule Ca2+ATPase (SERCA) stimulator which has been shown in animal studies to improves memory and cognition in Alzheimer’s, reduces dyskinesia in Parkinson’s, control blood sugar in diabetes, and improve cardiac function in heart failure.
After coming across Dr. Dahl’s journal articles during her research, Brunde contacted Dr. Dahl and they quickly developed a meaningful relationship centered around their mutual knowledge and passion for Ca2+ATPase. They have since jointed efforts to promote the education of both the public at large and the medical community regarding Ca2+ATPase, in addition to the development of drugs to target this enzyme. Dr. Dahl serves as an medical advisor and editor for the book and Brunde serves on the board of directors at Neurodon. Both hope to reduce suffering and save many lives through their efforts.
Recent articles related to Ca2+ATPase:
1. A new target for Alzheimer’s disease: A small molecule SERCA activator is neuroprotective in vitro and improves memory and cognition in APP/PS1 mice.
Krajnak K, Dahl R. Bioorg Med Chem Lett. 2018 May 15;28(9):1591-1594.
2. A new target for Parkinson’s disease: Small molecule SERCA activator CDN1163 ameliorates dyskinesia in 6-OHDA-lesioned rats.
Dahl R.Bioorg Med Chem. 2017 Jan 1;25(1):53-57.
3. Small Molecular Allosteric Activator of the Sarco/Endoplasmic Reticulum Ca2+-ATPase (SERCA) Attenuates Diabetes and Metabolic Disorders.
Kang S, Dahl R, Hsieh W, Shin A, Zsebo KM, Buettner C, Hajjar RJ, Lebeche D.
J Biol Chem. 2016 Mar 4;291(10):5185-98.
4. Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure.
Kho C, Lee A, Jeong D, Oh JG, Gorski PA, Fish K, Sanchez R, DeVita RJ, Christensen G, Dahl R, Hajjar RJ. Nat Commun. 2015 Jun 12;6:7229.
Lyle was raised with a practical, “rub what hurts” and “heal with plants”, approach to self-care learned from his parents and grandparents. He translated this foundation, via professional certifications in several manual and movement therapies and formal training in both Eastern and Western natural medicine, into a clinical practice of nearly 40 years and counting. Using nutrition, supplements, herbs, and manual therapies, he has helped countless people improve their health and wellbeing. In addition to his practice, Lyle has taught at the college, university, and professional levels for three decades, and has worked with Brunde Broady for the last ten years to better understand how to practically apply her Ca²+ATPase research to optimize health.
Karen Lacey is a bestselling author who’s worked with some of the largest and most established publishing firms in the world, including Penguin, McGraw Hill, Wiley, St. Martin’s Press, and AMACOM. Over the last decade, as a senior author for Kevin Anderson and Assoc. she has ghostwritten, edited, and doctored a plethora of books on behalf of her clients, several of which have become bestsellers.
Karen has lived and written throughout the world. She spent seven years as a wildlife photographer and writer in southern Africa, and after moving to London spent two years writing daily financial analyses for a boutique investment firm. She also made appearances on Sky Business News and Reuters TV and conducted daily commentaries on Bloomberg News. Karen has also lived in Argentina, Spain, Denmark, and Australia. She has written three novels, countless short stories, and is a 2011 graduate of the Odyssey Writer’s Workshop.